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Glycocholic acid, or cholylglycine, is a crystalline bile acid involved in the emulsification of . It occurs as a sodium salt in the bile of . It is a conjugate of cholic acid with glycine. Its anion is called glycocholate.
In a prospective study, positive associations were observed between prediagnostic plasma levels of seven conjugated bile acid metabolites, including glycocholic acid, and colon cancer risk. These findings support experimental data suggesting that high circulating bile acids promote colon cancer risk.
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